Ambre Bertholet, PhD

Postdoctoral Fellow
Kirichok Lab
+1 415 476-6734

Molecular Mechanisms of Mitochondrial Uncoupling and Themogenesis

Brown and Beige Fat


Mitochondrial Patch Clamp of Beige Adipocytes Reveals UCP1-Positive and UCP1-Negative Cells Both Exhibiting Futile Creatine Cycling.

Cell metabolism

Bertholet AM, Kazak L, Chouchani ET, Bogaczynska MG, Paranjpe I, Wainwright GL, Bétourné A, Kajimura S, Spiegelman BM, Kirichok Y

UCP1: A transporter for H+ and fatty acid anions.


Bertholet AM, Kirichok Y

Perinatal Licensing of Thermogenesis by IL-33 and ST2.


Odegaard JI, Lee MW, Sogawa Y, Bertholet AM, Locksley RM, Weinberg DE, Kirichok Y, Deo RC, Chawla A

Loss of functional OPA1 unbalances redox state: implications in dominant optic atrophy pathogenesis.

Annals of clinical and translational neurology

Millet AM, Bertholet AM, Daloyau M, Reynier P, Galinier A, Devin A, Wissinguer B, Belenguer P, Davezac N

Mitochondrial fusion/fission dynamics in neurodegeneration and neuronal plasticity.

Neurobiology of disease

Bertholet AM, Delerue T, Millet AM, Moulis MF, David C, Daloyau M, Arnauné-Pelloquin L, Davezac N, Mils V, Miquel MC, Rojo M, Belenguer P

OPA1 loss of function affects in vitro neuronal maturation.

Brain : a journal of neurology

Bertholet AM, Millet AM, Guillermin O, Daloyau M, Davezac N, Miquel MC, Belenguer P

OPA1 (dys)functions.

Seminars in cell & developmental biology

Landes T, Leroy I, Bertholet A, Diot A, Khosrobakhsh F, Daloyau M, Davezac N, Miquel MC, Courilleau D, Guillou E, Olichon A, Lenaers G, Arnauné-Pelloquin L, Emorine LJ, Belenguer P

Involvement of hippocampal CA3 K(ATP) channels in contextual memory.


Betourne A, Bertholet AM, Labroue E, Halley H, Sun HS, Lorsignol A, Feng ZP, French RJ, Penicaud L, Lassalle JM, Frances B