Ambre Bertholet, PhD

Postdoctoral Fellow
Kirichok Lab
+1 415 476-6734

Molecular Mechanisms of Mitochondrial Uncoupling and Themogenesis

Brown and Beige Fat

Publications: 

Patch-Clamp Analysis of the Mitochondrial H+ Leak in Brown and Beige Fat.

Frontiers in physiology

Bertholet AM, Kirichok Y

Molecular Identity and Regulatory Mechanisms of the Mitochondrial Uncoupling Protein of Non-Adipose Tissues.

Biophysical journal

Ambre M. Bertholet, Edward T. Chouchani, Lawrence Kazak, Alessia Angelin, Andriy Fedorenko, Jonathan Z. Long, Sara Vidoni, Ryan Garrity, Joonseok Cho, Naohiro Terada, Douglas Wallace, Bruce M. Spiegelman, Yuriy V. Kirichok

H+ transport is an integral function of the mitochondrial ADP/ATP carrier.

Nature

Bertholet AM, Chouchani ET, Kazak L, Angelin A, Fedorenko A, Long JZ, Vidoni S, Garrity R, Cho J, Terada N, Wallace DC, Spiegelman BM, Kirichok Y

The Mechanism FA-Dependent H+ Transport by UCP1.

Handbook of experimental pharmacology

Bertholet AM, Kirichok Y

Perinatal Licensing of Thermogenesis by IL-33 and ST2.

Cell

Odegaard JI, Lee MW, Sogawa Y, Bertholet AM, Locksley RM, Weinberg DE, Kirichok Y, Deo RC, Chawla A

Mitochondrial Patch Clamp of Beige Adipocytes Reveals UCP1-Positive and UCP1-Negative Cells Both Exhibiting Futile Creatine Cycling.

Cell metabolism

Bertholet AM, Kazak L, Chouchani ET, Bogaczynska MG, Paranjpe I, Wainwright GL, Bétourné A, Kajimura S, Spiegelman BM, Kirichok Y

UCP1: A transporter for H+ and fatty acid anions.

Biochimie

Bertholet AM, Kirichok Y

Perinatal Licensing of Thermogenesis by IL-33 and ST2.

Cell

Odegaard JI, Lee MW, Sogawa Y, Bertholet AM, Locksley RM, Weinberg DE, Kirichok Y, Deo RC, Chawla A