Junji Suzuki, MD, PhD

Postdoctoral Fellow
Kirichok Lab
+1 415 476-6734

Mitochondrial Optogenetics

Mitochondrial Transport of Anions

Publications: 

Red fluorescent CEPIA indicators for visualization of Ca2+ dynamics in mitochondria.

Scientific reports

Kanemaru K, Suzuki J, Taiko I, Iino M

Insights into channel modulation mechanism of RYR1 mutants using Ca2+ imaging and molecular dynamics.

The Journal of general physiology

Yamazawa T, Ogawa H, Murayama T, Yamaguchi M, Oyamada H, Suzuki J, Kurebayashi N, Kanemaru K, Oguchi K, Sakurai T, Iino M

Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and Cancers.

Cell reports

Chatterjee N, Pazarentzos E, Mayekar MK, Gui P, Allegakoen DV, Hrustanovic G, Olivas V, Lin L, Verschueren E, Johnson JR, Hofree M, Yan JJ, Newton BW, Dollen JV, Earnshaw CH, Flanagan J, Chan E, Asthana S, Ideker T, Wu W, Suzuki J, Barad BA, Kirichok Y, Fraser JS, Weiss WA, Krogan NJ, Tulpule A, Sabnis AJ, Bivona TG

Efficient high-throughput screening by ER Ca2+ measurement to identify inhibitors of ryanodine receptor Ca2+-release channels.

Molecular pharmacology

Murayama T, Kurebayashi N, Ikegami-Yuasa M, Mori S, Suzuki Y, Akima R, Ogawa H, Suzuki J, Kanemaru K, Oyamada H, Kiuchi Y, Iino M, Kagechika H, Sakurai T

Genotype-Phenotype Correlations of Malignant Hyperthermia and Central Core Disease Mutations in the Central Region of the RYR1 Channel.

Human mutation

Murayama T, Kurebayashi N, Ogawa H, Yamazawa T, Oyamada H, Suzuki J, Kanemaru K, Oguchi K, Iino M, Sakurai T

Nitric Oxide-induced Activation of the Type 1 Ryanodine Receptor Is Critical for Epileptic Seizure-induced Neuronal Cell Death.

EBioMedicine

Mikami Y, Kanemaru K, Okubo Y, Nakaune T, Suzuki J, Shibata K, Sugiyama H, Koyama R, Murayama T, Ito A, Yamazawa T, Ikegaya Y, Sakurai T, Saito N, Kakizawa S, Iino M

Genetically Encoded Fluorescent Indicators for Organellar Calcium Imaging.

Biophysical journal

Suzuki J, Kanemaru K, Iino M

Visualization of Ca2+ Filling Mechanisms upon Synaptic Inputs in the Endoplasmic Reticulum of Cerebellar Purkinje Cells.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Okubo Y, Suzuki J, Kanemaru K, Nakamura N, Shibata T, Iino M

Neuronal Regulation of Schwann Cell Mitochondrial Ca(2+) Signaling during Myelination.

Cell reports

Ino D, Sagara H, Suzuki J, Kanemaru K, Okubo Y, Iino M

Divergent Activity Profiles of Type 1 Ryanodine Receptor Channels Carrying Malignant Hyperthermia and Central Core Disease Mutations in the Amino-Terminal Region.

PloS one

Murayama T, Kurebayashi N, Yamazawa T, Oyamada H, Suzuki J, Kanemaru K, Oguchi K, Iino M, Sakurai T

Imaging intraorganellar Ca2+ at subcellular resolution using CEPIA.

Nature communications

Suzuki J, Kanemaru K, Ishii K, Ohkura M, Okubo Y, Iino M